THCP and CBDP: are they the cannabinoids of the (near) future? (2024)

New substances are arriving on the cannabinoid market. The latest are THCP and CBDP. Their discovery is driving many medical researchers, but what are these new molecules? And how can you consume them safely? Find out all you need to know about THCP and CBDP, the new cannabinoids.

THCP and CBDP: recently discovered molecules

THCP (Delta-9 Tetrahydrocannabiphorol) and CBDP (Cannabidiphorol) are two minor cannabinoids discovered during research by a team of Italian researchers. In 2019, Professor Giuseppe Cannazza and his team of scientists discovered these two molecules in a university laboratory in Italy.

They detected THCP and CBDP completely by chance, during pharmaceutical research. These molecules are present in minute quantities in CBD. And their molecular chains are quite different from CBD and THC. The result is new substances and new effects.

These cannabinoids are naturally present in all varieties of hemp. But their concentrations are random, as some species may contain very little, while others have more.

FM2 is an Italian CBD variety with high THCP and CBDP levels. It has been used for research into therapeutic cannabis. These cannabinoids are cultivated by crossing certain THCP- and CBDP-rich varieties, including FM2.

To date,THCP and CBDP are the focus of medical research. They are substances that could further support the endocannabinoid system, and thus enhance the well-being of certain individuals.

What is CBDP?

CBDP has a very different molecular chain from CBD, which gives it different properties. It does, however, retain its anti-inflammatory and analgesic properties, which are recognized as being more powerful than those of simple CBD.

Thanks to its affinity with CB1 and CB2 receptors, it plays a key role in regulating physiological functions, interfering with all the body's systems: nervous, cardiovascular, digestive, endocrine and so on.

The advantage of this substance lies in its psychoactive inactivity . Unlike THC, CBDP has no psychological repercussions. CBDP therefore does not produce the psychoactive effects associated with the recreational use of cannabis.

It is therefore a promising candidate for exploration of its therapeutic benefits, since despite its notable potency, this substance does not trigger undesirable effects such as euphoria or mental confusion.

CBDP will also prove highly useful if it can demonstrate a better ability to reach the human endocannabinoid system than CBD. This means that there are a multitude of methods for relieving intense pain.

It would be highly possible for CBDP to have a better capacity for action than CBD. However, more research remains to be done.

What is THCP?

The chemical make-up of substance delta 9 – THCP is similar to THC, but with a slightly longer carbon side chain. While THC has 5 carbon atoms in its molecular structure, THCP has 7.

These few extra molecules enable it to increase its affinity with the CB1 and CB2 receptors present in our bodies. THCP reaches CB1 receptors 30 times faster than THC, and CB2 receptors 5 to 10 times faster.

Its elongated structure also enables THCP to bind more easily to the receptor, making it much more potent. Its effects may be felt more quickly than THC.

In other words, a strain containing 1% THCP could be more potent than one with 30% THC. There are no commercially available THCP-rich strains yet, but cannabis experiments are in full swing.

Many consumers with a high tolerance to THC could benefit from THCP, according to some opinions. THCP's potency could reduce cannabis consumption. But it could also provide intense relief for people suffering from chronic pain or insomnia.

THCP and CBDP action on the endocannabinoid system

Some cannabinoids, such as THC, CBN and CBG, are beginning to be the subject of much research, but THCP and CBDP have only recently been discovered. Studies are currently being carried out into the effects of these new substances, as well as into their well-being.

Initial studies have shown similarities between CBDP and CBD, as well as between THCP and THC. But their molecular chains are much longer than those of CBD and THC.

This molecular composition could facilitate assimilation by the body. Their extra atoms enable them to bind more tightly to endocannabinoid receptors. This means the molecules could be effective faster, longer and with more intense effects.

The endocannabinoid system corresponds to the absorption of cannabis or CBD molecules and their action on the body. It acts on several key points located in all parts of the body. It acts on the nervous system, digestion, inflammation, the cardiovascular system, hormone regulation (endocrine system)…

Like THC and CBD, THCP and CBDP could provide pain relief, reduce nausea, decrease inflammation, regulate appetite and improve living conditions for epileptics. The same applies to the side effects of THCP, which could cause lethargy, drowsiness and a powerful psychoactive action.

What we don't yet know about THCP and CBDP

THCP and CBDP are mainly the subject of extensive studies in the medical field, for use in pharmacopoeia. Preliminary studies on the pharmacological properties of CBDP suggest that it may have anti-inflammatory, analgesic and antioxidant effects.

There may be a link between neuronal activity and neurological disorders and diseases of the nervous system. CBDP could improve conditions for people suffering from neurodegenerative diseases (Parkinson's, Alzheimer's). But it could also support dermatological conditions (eczema, psoriasis) and prevent immunological disorders, including autoimmune diseases: type 1 diabetes, multiple sclerosis, polyarthritis, Crohn's disease…

THCP could also play an effective role in pain reduction, as well as in the field of addictology. Potential uses for THCP include the relief of chronic pain, the treatment of inflammation, the control of nausea and vomiting associated with chemotherapy, and support in the fight against certain neurological diseases such as epilepsy.

These phytocannabinoids have superior potential for action, and are generating a great deal of enthusiasm in the scientific community. Although research is still limited, THCP and CBDP are paving the way for new medical and recreational prospects.

Opinion THCP and CBDP: are they the new alternatives?

There aren't enough studies to estimate whether THCP and CBDP will be the new cannabinoids. For the time being, they can be found in some CBD stores, both physical and online.

So it's important to remain vigilant about the quantity present in CBD products. Remember that these two cannabinoids are extremely powerful and require a certain amount of care. It is strongly advised to consult a doctor, especially for those suffering from serious illnesses. And consume THCP and CBDP in small doses. Start small to assess the effects on your body.

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